(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid → 2-(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-N-[4-(4-isopropyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

反応式

[CH:20]([CH3:21])([CH3:22])[N:23]1[CH2:24][CH2:25][N:26]([CH2:29][c:30]2[c:31]([C:37]([F:38])([F:39])[F:40])[cH:32][c:33]([NH2:36])[cH:34][cH:35]2)[CH2:27][CH2:28]1.[n:1]1[cH:2][n:3](-[c:10]2[cH:11][cH:12][c:13]([CH2:16][C:17](=[O:18])[OH:19])[cH:14][cH:15]2)[c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12>>[n:1]1[cH:2][n:3](-[c:10]2[cH:11][cH:12][c:13]([CH2:16][C:17](=[O:19])[NH:36][c:33]3[cH:32][c:31]([C:37]([F:38])([F:39])[F:40])[c:30]([CH2:29][N:26]4[CH2:25][CH2:24][N:23]([CH:20]([CH3:21])[CH3:22])[CH2:28][CH2:27]4)[cH:35][cH:34]3)[cH:14][cH:15]2)[c:4]2[n:5][cH:6][cH:7][cH:8][c:9]12

参加物

反応物 2

HCID 53213084(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-acetic acid

HCID 574314454-(4-Isopropylpiperazin-1-ylmethyl)-3-trifluoromethyl-aniline

生成物 1

HCID 119934802-(4-Imidazo[4,5-b]pyridin-3-yl-phenyl)-N-[4-(4-isopropyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

出典と根拠

ORDレコード: ord-8fedce866e23434396f171f66f69d121
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…