反応式
[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][C:5]#[N:6].C#C.[CH:10]1[CH:15]=CC=[CH:12][CH:11]=1>[CH-]1C=CC=C1.[CH-]1C=CC=C1.[Co+2]>[CH3:1][N:2]([CH3:7])[CH2:3][CH2:4][C:5]1[CH:12]=[CH:11][CH:10]=[CH:15][N:6]=1参加物
5
反応条件
- 温度
- 170 °C
実験手順
1.0 gm. of cobaltocene (0.005 mole) and 71.5 gm. of β-dimethylaminopropionitrile (0.7 mole) was saturated with 12 atm. of acetylene at 20° C. (as in Example 13) and heated to 170° C. The admixture was stirred for another hour at a constant acetylene pressure of 12 atm. after a pressure drop to 11 atm. Upon distillative processing of the reaction product, 4.4 gm. of benzol, 5 gm. of β-dimethylaminoproprionitrile and 80.1 gm. of 2-(β-dimethylaminoethyl)-pyridine were obtained. This corresponded to a conversion of 93.0 percent of β-dimethylaminopropionitrile and a yield of 72.7 percent of 99.4 percent 2-(β-dimethylaminoethyl)-pyridine.
出典と根拠
- ORDレコード
- ord-c9fe307dc8d74ef39e99003f578008d8
- 出典データセット
- uspto-grants-1980_04
- 特許番号
- US04196287
関連ノート
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