化工社化工社 化学情報印刷レポート · 研究参考用
Ethanone, 2-chloro-1,2-diphenyl- → Thiazole, triphenyl-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanone, 2-chloro-1,2-diphenyl- | HCID 95343 | — |
| 反応物 | Thiobenzamide | HCID 683563 | — |
| 溶媒 | Isopropanol | HCID 3776 | — |
| 生成物 | Thiazole, triphenyl- | HCID 1712256 | — |
反応手順
Thiobenzamide (13.7 g, 0.10 mole) and desyl chloride (23.1 g, 0.10 mole) are heated under reflux in isopropyl alcohol (100 ml) for three hours. When the reaction mixture is cooled, the white solid precipitate formed is filtered off, washed twice with isopropyl alcohol, and dried. The yield of triphenylthiazole, m.p. 84°-85.5° C., is 21.5 g or 69%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04197306 |
| 出典データセット | uspto-grants-1980_04 |
| ORD ID | ord-3912ad2349f94687be5fa180fdf6869a |
| 出典メモ | uspto-grants-1980_04 |