Propargylamine → 1-Cyano-2-(2-propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene
反応式
S1C=CN=C1CSCCN.[C:11]([CH:13]=[C:14](OC)OC)#[N:12].[C:19]([CH:21]=[C:22](OC)[NH:23][CH2:24][CH2:25][S:26][CH2:27][C:28]1[S:29][CH:30]=[CH:31][N:32]=1)#[N:20].C(N)C#C>>[C:19]([CH:21]=[C:22]([NH:12][CH2:11][C:13]#[CH:14])[NH:23][CH2:24][CH2:25][S:26][CH2:27][C:28]1[S:29][CH:30]=[CH:31][N:32]=1)#[N:20]参加物
5
反応物 4
生成物 1
実験手順
When 2-[(thiazol-2-yl)methylthio]ethylamine is reacted with 1-cyano-2,2-bis(methoxy)ethylene [prepared according to the procedure described in J. Chem. Soc., (Suppl. Issue No. 1), S106-111 (1949)] and the resultant 1-cyano-2-methoxy-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene is reacted with propargylamine in the procedure of Example 1, the title compound is produced.