化工社化工社 化学情報印刷レポート · 研究参考用
Acetophenone → 1-(4-Methylphenyl)-3-phenylpropane-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetophenone | HCID 7410 | — |
| 反応物 | Methyl 2,5-dimethylbenzoate | HCID 273300 | — |
| 反応物 | Sodium Methoxide | HCID 10942334 | — |
| 溶媒 | O-Xylene | HCID 7237 | — |
| 生成物 | 1-(4-Methylphenyl)-3-phenylpropane-1,3-dione | HCID 781108 | — |
反応手順
Acetophenone (30 grams; 0,25 mol), methyl p-methyltoluate (136 grams; 1.0 mol), xylene (300 ml) and sodium methoxide (17.3 grams; 0.3 mol) were placed into a four-necked round bottom one liter flask equipped as in Example 1. The mixture was heated with stirring to 135°-140° C. and maintained there for 6 hours under a blanket of nitrogen. The procedure set forth in Example 1 was used to recover the desired product, benzoyl p-methylbenzoylmethane (40 grams; 67 weight percent yield) having a purity of 66%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05015777 |
| 出典データセット | uspto-grants-1991_05 |
| ORD ID | ord-7643653de6e9428088e520bee637b9e5 |
| 出典メモ | uspto-grants-1991_05 |