Benzaldehyde → 1-(Benzylideneamino)piperazine-2,3-dione

HRID 2051761

反応式

HRID 2051761 の反応式
[NH2:1][N:2]1[CH2:7][CH2:6][NH:5][C:4](=[O:8])[C:3]1=[O:9].[CH:10](=O)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(O)(=O)C>[CH:10](=[N:1][N:2]1[CH2:7][CH2:6][NH:5][C:4](=[O:8])[C:3]1=[O:9])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

参加物

4

反応物 2

HCID 240BenzaldehydeHCID 221847681-Aminopiperazine-2,3-dione

生成物 1

HCID 538480401-(Benzylideneamino)piperazine-2,3-dione収率 81.8%

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

1.3 pts. by wt. of 1-amino-2,3-dioxo-piperazine, 1.3 pts. by wt. of benzaldehyde and 7 pts. by vol. of glacial acetic acid are warmed to 90° for 90 minutes and then left at 5° for 30 minutes. The precipitate is filtered off, washed first with 3 pts. by vol. of glacial acetic acid and then with three times 10 pts. by vol. of ethyl acetate and dried over P2O5. 1.75 pts. by wt. (81.8% ) of 1-benzylideneamino-2,3-dioxo-piperazine of melting point 236°-240° C. are obtained.

後処理

  1. filtrationThe precipitate is filtered off
  2. washwashed first with 3 pts
  3. dry with materialby vol. of ethyl acetate and dried over P2O5

出典と根拠

ORDレコード
ord-67842b50b9f74f29bb02427072c33c45
出典データセット
uspto-grants-1980_01
特許番号
US04182762

関連ノート

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