Water → 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole

HRID 2051768ノート

反応式

HRID 2051768 の反応式
[CH3:1][S:2][C:3]1[NH:7][C:6]2[CH:8]=[C:9]3[C:14](=[CH:15][C:5]=2[N:4]=1)[CH:13]=[CH:12][CH:11]=[CH:10]3.SC[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1.O>C(O)C>[N:19]1[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=1[CH2:1][S:2][C:3]1[NH:4][C:5]2[CH:15]=[C:14]3[C:9](=[CH:8][C:6]=2[N:7]=1)[CH:10]=[CH:11][CH:12]=[CH:13]3

参加物

5

反応物 3

HCID 962WaterHCID 2560712-PyridinemethanethiolHCID 128720792-(methylthio)-1H-naphtho[2,3-d]imidazole

生成物 1

HCID 223941842-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole収率 81.7%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

0.45 g of 2-methylthio-1H-naphth[2,3-d]imidazole and 0.64 g of 2-mercaptomethylpyridine were heated for 40 hours under reflux in 10 ml of ethanol. 10 ml of water were added to the homogeneous solution and the precipitate formed was filtered off. 0.50 g of 2-[(2-pyridylmethyl)thio]-1H-naphth[2,3-d]imidazole having a m.p. of 170° was obtained.

後処理

  1. customthe precipitate formed
  2. filtrationwas filtered off

出典と根拠

ORDレコード
ord-8cffeb46b0b14b5395d8e0e24fdbc492
出典データセット
uspto-grants-1980_01
特許番号
US04182766

反応ノート

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