Formic Acid → N-[Dichlorophosphinyl]-3-phenoxybenzamide

HRID 2052138

反応式

HRID 2052138 の反応式
[O:1]([C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([NH2:13])=[O:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[P:17]([Cl:22])(Cl)(Cl)(Cl)[Cl:18].C(O)=[O:24]>C(Cl)(Cl)(Cl)Cl>[Cl:18][P:17]([Cl:22])([NH:13][C:11](=[O:12])[C:10]1[CH:14]=[CH:15][CH:16]=[C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH:9]=1)=[O:24]

参加物

5

反応物 3

HCID 284Formic AcidHCID 24819Phosphorus pentachlorideHCID 166186253-Phenoxybenzamide

生成物 1

HCID 20378783N-[Dichlorophosphinyl]-3-phenoxybenzamide

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture containing 21.3 g (0.1 mole) of 3-phenoxybenzamide, 20.8 g (0.1 mole) of phosphorus pentachloride and 250 ml of Ar carbon tetrachloride was heated at 70° for 30 min. The resulting solution was cooled to 30° and 4.7 g (0.1 mole) of 97% formic acid added dropwise. Stirring was continued for 20 min., the reaction was filtered, washed with AR carbon tetrachloride and air-dried to give 31 g, m.p. 122°-125°.

後処理

  1. temperaturewas heated at 70° for 30 min
  2. temperatureThe resulting solution was cooled to 30°
  3. filtrationthe reaction was filtered
  4. washwashed with AR carbon tetrachloride
  5. customair-dried
  6. customto give 31 g, m.p. 122°-125°

出典と根拠

ORDレコード
ord-4bd5ad77bc0d42bc847b585c59bfa4fb
出典データセット
uspto-grants-1980_01
特許番号
US04182881

関連ノート

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