Potassium Carbonate → HCID 68810790、化合物
反応式
[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=1)=[O:4].[ClH:13].Cl.[CH2:15]([N:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1)[C:16]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)=[O:17].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[ClH:1].[ClH:13].[ClH:1].[CH2:15]([N:24]1[CH2:29][CH2:28][N:27]([CH2:2][C:3]([NH:5][CH2:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=2)=[O:4])[CH2:26][CH2:25]1)[C:16]([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)=[O:17]参加物
5
実験手順
A mixture of 2-chloro-N-(pyridin-2-ylmethyl)acetamide (1.3 mmol), N-phenacyl piperazine dihydrochloride (1 mmol), and K2CO3 (8.75 mmol) in 30 ml of DMF was treated according to the general preparation 2 to give compound (IV-31), 0.7 g (60.45%), M+ 381.