Potassium Carbonate → HCID 69203949、化合物
反応式
[ClH:1].Cl.[CH3:3][O:4][C:5]1[CH:17]=[CH:16][C:8]([CH2:9][N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:7][CH:6]=1.[Cl:18][CH:19]([CH3:35])[C:20]([C:22]1[CH:31]=[CH:30][C:29]2[C:24](=[CH:25][CH:26]=[C:27]([O:33][CH3:34])[C:28]=2[Cl:32])[CH:23]=1)=[O:21].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[ClH:18].[ClH:1].[CH3:3][O:4][C:5]1[CH:6]=[CH:7][C:8]([CH2:9][N:10]2[CH2:15][CH2:14][N:13]([CH:19]([C:20]([C:22]3[CH:31]=[CH:30][C:29]4[C:24](=[CH:25][CH:26]=[C:27]([O:33][CH3:34])[C:28]=4[Cl:32])[CH:23]=3)=[O:21])[CH3:35])[CH2:12][CH2:11]2)=[CH:16][CH:17]=1参加物
5
実験手順
A mixture of N-(4-methoxybenzyl)piperazine dihydrochloride (0.35 g, 1.3 mmol), 2-chloro-1-(5-chloro-6-methoxynaphthalen-2-yl)propan-1-one (0.44 g, 1.57 mmol) and K2CO3 (0.65 g, 4.6 mmol) in 20 ml of DMF was treated according to general preparation 2 to give 0.4 g of compound (IV-31), yield 57%, mp 222-224° C. M+ 452.