Benzenesulfonyl chloride, 3,4-dichloro- → N-(2-benzoyl-4-chloro-phenyl)-3,4-dichloro-benzenesulfonamide

HRID 2056278

反応式

HRID 2056278 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[C:9]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:10].[Cl:17][C:18]1[CH:19]=[C:20]([S:25](Cl)(=[O:27])=[O:26])[CH:21]=[CH:22][C:23]=1[Cl:24]>>[C:9]([C:3]1[CH:4]=[C:5]([Cl:8])[CH:6]=[CH:7][C:2]=1[NH:1][S:25]([C:20]1[CH:21]=[CH:22][C:23]([Cl:24])=[C:18]([Cl:17])[CH:19]=1)(=[O:27])=[O:26])(=[O:10])[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

参加物

3

反応物 2

HCID 7383Benzenesulfonyl chloride, 3,4-dichloro-HCID 128702-Amino-5-chlorobenzophenone

生成物 1

HCID 11247684N-(2-benzoyl-4-chloro-phenyl)-3,4-dichloro-benzenesulfonamide

実験手順

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 115 mg of (2-amino-5-chloro-phenyl)-phenyl-methanone and 123 mg of 3,4-Dichloro-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 7.25 (d, 1H, J=8.8 Hz), 7.36-39 (m, 3H), 7.43-47 (m, 3H), 7.53 (dd, 1H, J=8.8 Hz, 2.4 Hz), 7.61 (m, 1H), 7.65 (m, 1H), 7.73 (d, 1H, J=8.8 Hz), 9.56 (s, 1H). MS: m/z 440.7 (M++1).

出典と根拠

ORDレコード
ord-3705a8c0dadd4d9cbfb08f5d04beb506
出典データセット
uspto-grants-2008_02
特許番号
US07335653B2

関連ノート

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