反応式
Cl[CH:2]([CH2:12][C:13]([Cl:16])([Cl:15])Cl)[C:3]([CH3:11])([CH3:10])[CH:4]([C:8]#[N:9])C(O)=O.C([O-])(=O)C.[Na+]>CN(C)C=O>[Cl:16][C:13]([Cl:15])=[CH:12][CH:2]1[C:3]([CH3:10])([CH3:11])[CH:4]1[C:8]#[N:9]参加物
4
反応条件
- 温度
- 145 °C
実験手順
4-Chloro-2-cyano-3,3-dimethyl-6,6,6-trichlorohexanoic acid (3.07 g) and sodium acetate (2.05 g; water-free) were dissolved in dimethyl formamide (8.0 ml). The solution was then stirred at 145° C. for 12 hours. The working-up procedure was the same as indicated in Example III and yielded 1.85 g of Compound A with purity 90%. Yield 86%.
出典と根拠
- ORDレコード
- ord-c3b5d3798f6a4b1d8a088b947a91d36d
- 出典データセット
- uspto-grants-1980_07
- 特許番号
- US04211720
関連ノート
読み込み中…