Acetylacetone → Ethanone, 1-(4-amino-2-methyl-5-(2-methylphenyl)-1H-pyrrol-3-yl)-

HRID 2057707ノート

反応式

HRID 2057707 の反応式
[NH2:1][CH:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH3:11])[C:3]#[N:4].[C:12]([CH2:15][C:16](=O)[CH3:17])(=[O:14])[CH3:13]>CO>[C:12]([C:15]1[C:3]([NH2:4])=[C:2]([C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[CH3:11])[NH:1][C:16]=1[CH3:17])(=[O:14])[CH3:13]

参加物

4

反応物 2

HCID 31261AcetylacetoneHCID 16767703α-Amino-2-methylbenzeneacetonitrile

生成物 1

HCID 41888Ethanone, 1-(4-amino-2-methyl-5-(2-methylphenyl)-1H-pyrrol-3-yl)-

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Starting from 2-amino-2-(o-tolyl)acetonitrile and acetylacetone, the open-chain intermediate compound is obtained, b.p. 120° C./0.2 mm Hg. The title compound is obtained in a 77% overall yield, m.p. 258° C. (from methanol).

後処理

  1. customthe open-chain intermediate compound is obtained

出典と根拠

ORDレコード
ord-60ce2f21490148d7a92de5501ea0789a
出典データセット
uspto-grants-1980_07
特許番号
US04212806

反応ノート

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