Hydrochloric Acid → HCID 86754565、化合物

HRID 2057886ノート

反応式

HRID 2057886 の反応式
[NH2:1][C@H:2]([C:5]([OH:7])=[O:6])[CH2:3][SH:4].[CH2:8](O)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[ClH:19]>C(OCC)(=O)C>[ClH:19].[CH2:8]([O:6][C:5](=[O:7])[C@H:2]([CH2:3][SH:4])[NH2:1])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 5862L-(+)-CysteineHCID 81741-Decanol

生成物 1

HCID 86754565HCID 86754565、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

L-Cysteine 157.4 g was added to 250 ml of decyl alcohol saturated with dry HCl. The mixture was heated to 150° for 6 h. The solution was cooled and was mixed with equal volume of ethyl acetate. The solution was cooled in a dry ice bath to give crystals. The crystals were filtered and were recrystallized from ethyl acetate, mp 96°-99° C., yield 100 g, IR (KBr) 1745 cm-1 ; NMR (CDCl3) δ.

後処理

  1. temperatureThe mixture was heated to 150° for 6 h
  2. temperatureThe solution was cooled
  3. temperatureThe solution was cooled in a dry ice bath
  4. customto give crystals
  5. filtrationThe crystals were filtered
  6. customwere recrystallized from ethyl acetate, mp 96°-99° C., yield 100 g, IR (KBr) 1745 cm-1

出典と根拠

ORDレコード
ord-e0530cded75144c28d833d437f388e40
出典データセット
uspto-grants-1980_07
特許番号
US04213978

反応ノート

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