Fumaric Acid → 1-Cyclooctylmethylimidazole hydrogen fumarate

HRID 2058447ノート

反応式

HRID 2058447 の反応式
[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[CH:9]1([CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[CH:19]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>C(O)C>[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[CH:9]1([CH2:17][N:18]2[CH:22]=[CH:21][N:20]=[CH:19]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

参加物

4

反応物 2

HCID 444972Fumaric AcidHCID 205502381-Cyclooctylmethylimidazole

生成物 1

HCID 205502371-Cyclooctylmethylimidazole hydrogen fumarate収率 71.9%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

A solution of fumaric acid (0.22 g) in hot ethanol (10 ml) was added to a solution of 1 -cyclooctylmethyl imidazole (0.38 g) in ethanol (4 ml). After boiling for 10 minutes the solution was evaporated to afford a white solid. Recrystallisation from ethyl acetate afforded 1-cyclooctylmethylimidazole hydrogen fumarate (0.42 g) as white needles, m.p. 147° to 148° C.

後処理

  1. customthe solution was evaporated
  2. customto afford a white solid
  3. customRecrystallisation from ethyl acetate

出典と根拠

ORDレコード
ord-e96747ec888f4ddc9acd75a8341803fe
出典データセット
uspto-grants-1982_03
特許番号
US04317830

反応ノート

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