HCID 86738258、化合物 → [(5,6-dichloro-3-oxo-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]acetic acid
反応式
ClC1C(Cl)=C(OCC(OC(C)(C)C)=O)C=C2C=1C1C(CC)(C2)CCC(=O)C=1.[Cl:28][C:29]1[C:41]([Cl:42])=[C:40]([O:43][CH2:44][C:45]([O:47]C(C)(C)C)=[O:46])[CH:39]=[C:38]2[C:30]=1[C:31]1[C:36]([CH2:52][CH2:53][CH3:54])([CH2:37]2)[CH2:35][CH2:34][C:33](=[O:55])[CH:32]=1>>[Cl:28][C:29]1[C:41]([Cl:42])=[C:40]([O:43][CH2:44][C:45]([OH:47])=[O:46])[CH:39]=[C:38]2[C:30]=1[C:31]1[C:36]([CH2:52][CH2:53][CH3:54])([CH2:37]2)[CH2:35][CH2:34][C:33](=[O:55])[CH:32]=1参加物
3
実験手順
Carrying out a reaction as described in Example 53, Step B, except that the tert.-butyl [(5,6-dichloro-9a-ethyl-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]acetate is replaced by an equimolar amount of tert.-butyl [(5,6-dichloro-3-oxo-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]acetate, thereby is obtained [(5,6-dichloro-3-oxo-9a-propyl-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]acetic acid.
後処理
- customCarrying out a reaction