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Sulfuric Acid → 1,3-dimethyl-4-nitro-1H-pyrazole-5-carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile | HCID 96507 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 1,3-dimethyl-4-nitro-1H-pyrazole-5-carboxamide | HCID 1229764 | — |
反応手順
27.2 g of 1,3-dimethyl-4-nitropyrazole-5-carbonitrile and 65 ml of concentrated sulfuric acid are stirred at 80° C. for 6 hours. The mixture is poured into 700 g of ice and water, and the precipitate is filtered off and suspended in ice-water; the suspension is neutralized with sodium bicarbonate to yield 27.3 g of 1,3-dimethyl-4-nitropyrazole-5-carboxamide, mp 164° to 165° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04317823 |
| 出典データセット | uspto-grants-1982_03 |
| ORD ID | ord-58589026adbf4087aa1210eba6aabe36 |
| 出典メモ | uspto-grants-1982_03 |