Acetone → HCID 12962350、化合物

HRID 2059112ノート

反応式

HRID 2059112 の反応式
[C:1]1([CH:7]2[NH:11][CH2:10][CH2:9][S:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CC(C)=O.C(N(CC)CC)C.[Cl:23][CH:24]([Cl:28])[C:25](Cl)=[O:26]>O>[C:1]1([CH:7]2[N:11]([C:25](=[O:26])[CH:24]([Cl:28])[Cl:23])[CH2:10][CH2:9][S:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

6

反応物 4

HCID 180AcetoneHCID 6593Dichloroacetyl chlorideHCID 8471TriethylamineHCID 207062-Phenylthiazolidine

生成物 1

HCID 12962350HCID 12962350、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Five (5) grams of 2-phenyl thiazolidine was dissolved in 50 ml. of acetone, 3.1 g. of triethylamine was added and the mixture stirred in a room temperature water bath, while 4.4 g. of dichloroacetyl chloride was added dropwise. The mixture was allowed to stand for about 30 minutes and then poured into water, extracted with methylene chloride, separated, dried over magnesium sulfate, and the solvent stripped under vacuum. There was obtained a yield of 7.3 g. of an oil, the title compound, ND30 =1.5836.

後処理

  1. extractionextracted with methylene chloride
  2. customseparated
  3. dry with materialdried over magnesium sulfate
  4. customThere was obtained a yield of 7.3 g

出典と根拠

ORDレコード
ord-638d2d11e1034966beb0d7c0c17c56e7
出典データセット
uspto-grants-1982_03
特許番号
US04322240

反応ノート

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