Aniline → HCID 12806745、化合物

HRID 2059188ノート

反応式

HRID 2059188 の反応式
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[Cl:12])[N:5]=[CH:4][N:3]=1.[NH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(O)C>[ClH:1].[NH:13]([C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][C:10]=2[Cl:12])[N:5]=[CH:4][N:3]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

4

反応物 2

HCID 6115AnilineHCID 2479114,5-Dichloroquinazoline

生成物 1

HCID 12806745HCID 12806745、化合物収率 46%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A solution of 3.0 g of 4,5-dichloroquinazoline and 1.4 g of aniline in 20 ml of ethanol was heated, whereupon a violet reaction occurred and the reaction mixture solidified. After cooling, the solidified product was collected and recrystallized from ethanol to give 1.8 g (yield 46%) of the desired Compound No. 2 in the form of a pale yellow powder melting at 263°-267° C. (with decomposition).

後処理

  1. temperatureAfter cooling
  2. customthe solidified product was collected
  3. customrecrystallized from ethanol

出典と根拠

ORDレコード
ord-372d0384dd0a4ccda59ee2b7da604dc4
出典データセット
uspto-grants-1982_03
特許番号
US04322420

反応ノート

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