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2,6-Dimethoxybenzoyl chloride → 2,6-Dimethoxy-N-(4-(4-(trifluoromethyl)phenyl)-5-isoxazolyl)benzamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dimethoxybenzoyl chloride | HCID 74810 | — |
| 反応物 | 4-(4-(Trifluoromethyl)phenyl)-5-aminoisoxazole | HCID 20546740 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 2,6-Dimethoxy-N-(4-(4-(trifluoromethyl)phenyl)-5-isoxazolyl)benzamide | HCID 13035564 | — |
反応手順
4-(4-(Trifluoromethyl)phenyl)-5-aminoisoxazole (1.0 g) and 2,6-dimethoxybenzoylchloride (2 g) were refluxed in 100 ml. toluene for 3 hours. The reaction mixture was cooled and the final product was then collected and recrystallized from ethanol, m.p. 199°-201° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04322429 |
| 出典データセット | uspto-grants-1982_03 |
| ORD ID | ord-680c61f813ff4726bed668b4b9331c3a |
| 出典メモ | uspto-grants-1982_03 |