4-Fluorophenylboronic acid → 6-(4-Fluorophenyl)pyridin-3-OL
反応式
Br[C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][N:3]=1.[F:9][C:10]1[CH:15]=[CH:14][C:13](B(O)O)=[CH:12][CH:11]=1>>[F:9][C:10]1[CH:15]=[CH:14][C:13]([C:2]2[N:3]=[CH:4][C:5]([OH:8])=[CH:6][CH:7]=2)=[CH:12][CH:11]=1参加物
3
実験手順
The title compound was prepared according to the method described for Preparation 17 using 2-bromo-5-hydroxypyridine and 4-fluorophenylboronic acid to afford the title compound as an off-white solid (270 mg, 51%)
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-79d791ec564f4382b84e1f97d5c97442
- 出典データセット
- uspto-grants-2012_10
- 特許番号
- US08278343B2
反応ノート
読み込み中…