3-Methoxybenzenethiol → 3-(2-Fluoro-3-aminobenzyl)-7-methyloxy-4-methyl-2-oxo-2H-1-benzothiopyran
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([SH:9])[CH:6]=[CH:7][CH:8]=1.C([O:12][C:13](=O)[CH:14]([CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([NH2:25])[C:20]=1[F:26])[C:15](=O)[CH3:16])C>>[F:26][C:20]1[C:21]([NH2:25])=[CH:22][CH:23]=[CH:24][C:19]=1[CH2:18][C:14]1[C:13](=[O:12])[S:9][C:5]2[CH:4]=[C:3]([O:2][CH3:1])[CH:8]=[CH:7][C:6]=2[C:15]=1[CH3:16]参加物
3
実験手順
The title compound was synthesized using 3-methyloxy-benzenethiol and 2-(2-fluoro-3-aminobenzyl)-3-oxobutanoic acid ethyl ester under the same conditions as in the manufacturing example for compound 5d-0-4S1.
出典と根拠
- ORDレコード
- ord-3617c94cb92c4bfea4961303eb16d915
- 出典データセット
- uspto-grants-2012_10
- 特許番号
- US08278465B2
反応ノート
読み込み中…