Pentadecalactone → 15-Bromopentadecanoic acid

HRID 2061917

反応式

HRID 2061917 の反応式
S(=O)(=O)(O)O.Br.[C:7]1(=[O:23])[O:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1.[Br:24]CCCCCCCCCCCCCCCOCCCCCCCCCCCCCCC(O)=O>C(O)(=O)C>[Br:24][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][C:7]([OH:22])=[O:23]

参加物

5

反応物 3

HCID 235414PentadecalactoneHCID 86639474Sulfuric acid hydrogen bromideHCID 8663947515-(15-Bromopentadecyloxy)pentadecanoic acid

生成物 1

HCID 55229615-Bromopentadecanoic acid

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

The present reaction can be carried out in the presence of acetic acid and can be performed by using acetic acid as a solvent. As described in the above Non-patent Document 11, when concentrated sulfuric acid-hydrogen bromide acid is used and 15-pentadecanolide is reacted, for example, 15-(15-bromopentadecyloxy)pentadecanoic acid, which is difficult to get separated from the target compound 15-bromopentadecanoic acid, is produced as a byproduct. As a result, it becomes difficult to obtain highly pure 15-bromopentadecanoic acid.

後処理

  1. customThe present reaction
  2. customto get
  3. customseparated from the target compound 15-bromopentadecanoic acid
  4. customis produced as a byproduct

出典と根拠

ORDレコード
ord-e1718c7d159f4af1a81fa7a5cc8e7d71
出典データセット
uspto-grants-2012_10
特許番号
US08283482B2

関連ノート

読み込み中…