Ammonia → 6-Amino-3-methoxy-2-pyrazinecarboxamide
反応式
[NH2:1][C:2]1[N:7]=[C:6]([C:8](OC)=[O:9])[C:5]([O:12][CH3:13])=[N:4][CH:3]=1.[NH3:14]>CO>[NH2:1][C:2]1[N:7]=[C:6]([C:8]([NH2:14])=[O:9])[C:5]([O:12][CH3:13])=[N:4][CH:3]=1参加物
4
実験手順
In 70 mL of methanol is dissolved 3.50 g of methyl 6-amino-3-methoxy-2-pyrazinecarboxylate. Gaseous ammonia is introduced to saturate the solution with ammonia. The solution is stirred at ambient temperature for 14 hours. The solvent is distilled off from the reaction mixture under reduced pressure to obtain 3.1 g of 6-amino-3-methoxy-2-pyrazinecarboxamide.
後処理
- concentrationto saturate the solution with ammonia
- distillationThe solvent is distilled off from the reaction mixture under reduced pressure
出典と根拠
- ORDレコード
- ord-d6253dc31ef84896a1e16e8c6a29b2af
- 出典データセット
- uspto-grants-2012_10
- 特許番号
- USRE043748E1
反応ノート
読み込み中…