1-Methyl-1H-1,2,4-triazol-3-amine → 2-(4-Methyl-imidazol-1-yl)-5-(1-methyl-1H-[1,2,4]triazol-3-ylamino)-benzonitrile

HRID 2063633ノート

反応式

HRID 2063633 の反応式
Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH3:16][N:17]1[CH:21]=[N:20][C:19]([NH2:22])=[N:18]1>>[CH3:15][C:13]1[N:12]=[CH:11][N:10]([C:5]2[CH:4]=[CH:3][C:2]([NH:22][C:19]3[N:20]=[CH:21][N:17]([CH3:16])[N:18]=3)=[CH:9][C:6]=2[C:7]#[N:8])[CH:14]=1

参加物

3

反応物 2

HCID 5665031-Methyl-1H-1,2,4-triazol-3-amineHCID 669615175-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile

生成物 1

HCID 593240592-(4-Methyl-imidazol-1-yl)-5-(1-methyl-1H-[1,2,4]triazol-3-ylamino)-benzonitrile

実験手順

Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-methyl-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a colorless solid (Yield=36%). MS ISP (m/e): 280.1 (100) [(M+H)+].

後処理

  1. customPrepared in analogy to example 1b)

出典と根拠

ORDレコード
ord-3845151f59204174a11a2c7f998fa0cc
出典データセット
uspto-grants-2012_10
特許番号
US08288403B2

反応ノート

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