3-Benzyl-1,2,4-thiadiazol-5-amine → 5-(3-Benzyl-[1,2,4]thiadiazol-5-ylamino)-2-(4-methyl-imidazol-1-yl)-benzonitrile
反応式
Br[C:2]1[CH:3]=[CH:4][C:5]([N:10]2[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]2)=[C:6]([CH:9]=1)[C:7]#[N:8].[CH2:16]([C:23]1[N:27]=[C:26]([NH2:28])[S:25][N:24]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([C:23]1[N:27]=[C:26]([NH:28][C:2]2[CH:3]=[CH:4][C:5]([N:10]3[CH:14]=[C:13]([CH3:15])[N:12]=[CH:11]3)=[C:6]([CH:9]=2)[C:7]#[N:8])[S:25][N:24]=1)[C:17]1[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1参加物
3
実験手順
Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 3-benzyl-[1,2,4]thiadiazol-5-ylamine. The title compound was obtained as a white solid (Yield=21%). MS ISP (m/e): 373.1 (100) [(M+H)+].
後処理
- customPrepared in analogy to example 1b)
出典と根拠
- ORDレコード
- ord-eb1ef3a7de084dd48688ea27858b1ab9