Hydrochloric Acid → HCID 57423922、化合物
反応式
[F:1][CH:2]([F:27])[O:3][C:4]1[CH:5]=[CH:6][C:7]2[NH:11][C:10](=[O:12])[N:9]([CH:13]3[CH2:18][CH2:17][N:16](C(OC(C)(C)C)=O)[CH2:15][CH2:14]3)[C:8]=2[CH:26]=1.[ClH:28]>CO.C(O)C>[ClH:28].[F:27][CH:2]([F:1])[O:3][C:4]1[CH:5]=[CH:6][C:7]2[NH:11][C:10](=[O:12])[N:9]([CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[C:8]=2[CH:26]=1参加物
5
実験手順
A solution of 1,1-dimethylethyl 4-{6-[(difluoromethyl)oxy]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-piperidinecarboxylate (D53, 0.54 g) in methanol (5 ml) was treated with a saturated solution of hydrogen chloride in ethanol (5 ml). The mixture was stirred for 1 hour when the solvent was removed to give the title compound as a white solid (0.45 g). Mass Spectrum 284 M+H+