4-(Trifluoromethyl)cinnamic acid → (E)-N-[1-(5-Acetyl-furan-2-ylmethyl)-1H-pyrazol-3-yl]-3-(4-trifluoromethyl-phenyl)-acrylamide
反応式
[CH3:1][C:2]1([C:7]2[O:11][C:10]([CH2:12][N:13]3[CH:17]=[CH:16][C:15]([NH2:18])=[N:14]3)=[CH:9][CH:8]=2)[O:6]CCO1.[F:19][C:20]([F:33])([F:32])[C:21]1[CH:26]=[CH:25][C:24](/[CH:27]=[CH:28]/[C:29](O)=[O:30])=[CH:23][CH:22]=1>>[C:2]([C:7]1[O:11][C:10]([CH2:12][N:13]2[CH:17]=[CH:16][C:15]([NH:18][C:29](=[O:30])/[CH:28]=[CH:27]/[C:24]3[CH:23]=[CH:22][C:21]([C:20]([F:32])([F:33])[F:19])=[CH:26][CH:25]=3)=[N:14]2)=[CH:9][CH:8]=1)(=[O:6])[CH3:1]参加物
3
実験手順
Following general procedure B followed by either C or D, starting from 1-[5-(2-methyl-[1,3]dioxolan-2-yl)-furan-2-ylmethyl]-1H-pyrazol-3-ylamine and (E)-3-(4-trifluoromethyl-phenyl)-acrylic acid.
出典と根拠
- ORDレコード
- ord-88c7424150c84ba7a83cfcca839e04e3
- 出典データセット
- uspto-grants-2012_10
- 特許番号
- US08288419B2
反応ノート
読み込み中…