化工社化工社 化学情報印刷レポート · 研究参考用
Glycine → 2-(Carboxymethyl-amino)-6-chloro-quinoline-3-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glycine | HCID 750 | — |
| 反応物 | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| 生成物 | 2-(Carboxymethyl-amino)-6-chloro-quinoline-3-carboxylic acid | HCID 67358680 | 52% |
反応手順
In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with glycine to provide the title compound in 52% yield as yellow needles (recrystallization from EtOH/water).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08288549B2 |
| 出典データセット | uspto-grants-2012_10 |
| ORD ID | ord-a0df76e0cc97404bb4d88e5753b5f061 |
| 出典メモ | uspto-grants-2012_10 |