Butanal → Benzyl-((E)-but-1-enyl)-amine

HRID 2066883ノート

反応式

HRID 2066883 の反応式
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:9](=O)[CH2:10][CH2:11][CH3:12].[OH-].[K+]>>[CH2:1]([NH:8]/[CH:9]=[CH:10]/[CH2:11][CH3:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 3

HCID 261ButanalHCID 7504BenzylamineHCID 14797Potassium Hydroxide

生成物 1

HCID 15360338Benzyl-((E)-but-1-enyl)-amine収率 74.4%

実験手順

To benzylamine (5.46 mL, 50 mmol), at 0° C., was added butyraldehyde (4.51 mL, 50 mmol). The mixture was warmed to room temperature and KOH (1.5 g) was added. The mix was stirred at room temperature for 15 minutes, the water was removed and 0.5 g of KOH was added. The mixture was stirred at room temperature overnight and filtered to remove the KOH to yield 6 g (74%) of 62a.

後処理

  1. customthe water was removed
  2. addition0.5 g of KOH was added
  3. stirringThe mixture was stirred at room temperature overnight
  4. filtrationfiltered
  5. customto remove the KOH

出典と根拠

ORDレコード
ord-98abbb7e88b24a96beaa2127597d52bf
出典データセット
uspto-grants-2012_10
特許番号
US08293729B2

反応ノート

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