Hydrochloric Acid → HCID 68412119、化合物

HRID 2070147ノート

反応式

HRID 2070147 の反応式
[NH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[CH:8]([NH:13]C(=O)C)[CH2:7]2.[ClH:17]>>[ClH:17].[ClH:17].[NH2:13][CH:8]1[CH2:7][C:6]2[C:11](=[C:2]([NH2:1])[CH:3]=[CH:4][CH:5]=2)[NH:10][C:9]1=[O:12]

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 59620340HCID 59620340、化合物

生成物 1

HCID 68412119HCID 68412119、化合物

反応条件

温度
110 °C

実験手順

N-(8-Amino-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)acetamide (8.4 g) was added to concentrated hydrochloric acid (84 mL), and the mixture was heated at 110° C. for three hours while being stirred, followed by stirring under cooling on ice. The formed precipitates were recovered through filtration, and the thus-obtained solid was washed with ethanol, followed by drying, whereby the title compound (9.17 g) was yielded.

後処理

  1. stirringby stirring
  2. temperatureunder cooling on ice
  3. customThe formed precipitates
  4. filtrationwere recovered through filtration
  5. washthe thus-obtained solid was washed with ethanol
  6. customby drying

出典と根拠

ORDレコード
ord-65d73bdbd2574308bf8b281452ae0ae2
出典データセット
uspto-grants-2012_10
特許番号
US08299255B2

反応ノート

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