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Ethanol → o-Tolyl thiosemicarbazide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | Ammonium thiocyanate | HCID 15666 | — |
| 反応物 | o-Tolylhydrazinium(1+) chloride | HCID 71554 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | o-Tolyl thiosemicarbazide | HCID 1490896 | — |
反応手順
A mixture of 15.9 g. (0.1 moles) of o-tolylhydrazine hydrochloride, 15.2 g. (0.2 moles) of ammonium thiocyanate, 300 ml. of ethanol and 30 ml. of water are heated at reflux temperature for 24 hours, the solvent is removed by distillation at atmospheric pressure, and sufficient water added to cause precipitation. The aqueous suspension is filtered and the solid residue recrystallized from aqueous ethanol affording 15 g. (85%) of 1-(o-tolyl)-3-thiosemicarbazide, m.p. 158°-160° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04046753 |
| 出典データセット | uspto-grants-1977_09 |
| ORD ID | ord-99d48bbfe556493a9025b89db86312d9 |
| 出典メモ | uspto-grants-1977_09 |