4-Isopropoxycarbonylamino-2-nitroaniline → 1,2-Diamino-4-isopropoxycarbonylaminobenzene

HRID 2071797ノート

反応式

HRID 2071797 の反応式
[N+:1]([C:4]1[CH:10]=[C:9]([NH:11][C:12]([O:14][CH:15]([CH3:17])[CH3:16])=[O:13])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-])=O.[H][H]>CO.[Pt]=O>[NH2:6][C:5]1[CH:7]=[CH:8][C:9]([NH:11][C:12]([O:14][CH:15]([CH3:16])[CH3:17])=[O:13])=[CH:10][C:4]=1[NH2:1]

参加物

5

反応物 2

HCID 126780374-Isopropoxycarbonylamino-2-nitroanilineHCID 178418361HCID 178418361、化合物2 回

生成物 1

HCID 126780381,2-Diamino-4-isopropoxycarbonylaminobenzene収率 66.3%

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 887Methanol溶媒

実験手順

A mixture of a solution of 2-nitro-4-isopropoxycarbonylaminoaniline (17.9 g, 0.075 mole) in methanol (450 ml) and platinum oxide (1.0 g) was shaken in an atmosphere of hydrogen at atmospheric pressure and laboratory temperature for several hours, during which time 5.04 liters of hydrogen were absorbed. The mixture was filtered, and the methanol removed in vacuo and the dark solid residue recrystallised from benzene to give 1,2-diamino-4-isopropoxycarbonylaminobenzene (10.4 g), m.p. 108°-110° C.

後処理

  1. customwere absorbed
  2. filtrationThe mixture was filtered
  3. customthe methanol removed in vacuo
  4. customthe dark solid residue recrystallised from benzene

出典と根拠

ORDレコード
ord-22ab45fac708435cae7f3fe6b69fef14
出典データセット
uspto-grants-1977_09
特許番号
US04048326

反応ノート

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