Water → HCID 55284641、化合物
反応式
[CH2:1]([CH2:4][NH:5][C:6]([CH3:10])([CH3:9])[C:7]#[N:8])[CH:2]=[CH2:3].O>C1C=CC=CC=1>[CH2:1]([CH2:4][NH:5][C:6]([CH3:10])([CH3:9])[CH2:7][NH2:8])[CH:2]=[CH2:3]参加物
4
実験手順
2-Allylmethylamino-2-methylpropionitrile (1.3 g.,) in benzene (20 ml., dry) was added dropwise to a stirred solution of sodium dihydro-bis [2-methoxy-ethoxy]aluminate (6.7 g.,) in benzene (30 ml., dry) under an atmosphere of nitrogen and stirred overnight. The excess reducing agent was decomposed by the dropwise addition of water. The phases were separated, the organic phase was washed with water, the aqueous phase was washed with benzene and the combined organic extract was dried (MgSO4) and the solvent was removed in vacuo to give a pale yellow liquid (1.8 g.). Distillation at 80°-90°/15 mm. gave 2-allylmethylamino-2-methylpropylamine as a colourless liquid (0.8 g., 60%).
後処理
- customThe phases were separated
- washthe organic phase was washed with water
- washthe aqueous phase was washed with benzene
- extractionthe combined organic extract
- dry with materialwas dried (MgSO4)
- customthe solvent was removed in vacuo
- customto give a pale yellow liquid (1.8 g.)
- distillationDistillation at 80°-90°/15 mm
出典と根拠
- ORDレコード
- ord-815a6304e27f443d82124404fdd0590b
- 出典データセット
- uspto-grants-1977_09
- 特許番号
- US04049663
反応ノート
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