Acetic Acid → 3-Benzylmercapto-4-carboxy benzaldehyde

HRID 2072304

反応式

HRID 2072304 の反応式
[CH2:1]([S:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][C:16]=1[C:17]([O:19]C)=[O:18])[CH:12]=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[K+].C(O)(=O)C>CO.O>[CH2:1]([S:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][C:16]=1[C:17]([OH:19])=[O:18])[CH:12]=[O:13])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

6

反応物 3

HCID 176Acetic AcidHCID 14797Potassium HydroxideHCID 538686323-Benzylmercapto-4-carbomethoxy benzaldehyde

生成物 1

HCID 539168353-Benzylmercapto-4-carboxy benzaldehyde収率 95.6%

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 962Water溶媒2 回

実験手順

To a boiling solution of 27.5 g of 3-benzylmercapto-4-carbomethoxy benzaldehye in 250 ml of methanol is added a solution of 7 g of potassium hydroxide in 24 ml of water. The reaction mixture is refluxed for 3-4 hours, then water is added to a volume of 1 liter. 10 Ml of acetic acid is added and the thus-obtained slurry is cooled, filtered, washed with water and air-dried to yield 25 g of 3-benzylmercapto-4-carboxy benzaldehyde, a yellow powder, having a melting point of 182°-190° C.

後処理

  1. temperatureThe reaction mixture is refluxed for 3-4 hours
  2. temperaturethe thus-obtained slurry is cooled
  3. filtrationfiltered
  4. washwashed with water
  5. customair-dried

出典と根拠

ORDレコード
ord-cf23b0e5e7734050a447b4c446f91e05
出典データセット
uspto-grants-1977_09
特許番号
US04051148

関連ノート

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