化工社化工社 化学情報印刷レポート · 研究参考用
Ethanolamine → 2-Carboxy-5-methylpyrazine 4-oxide ethanolamine salt
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanolamine | HCID 700 | — |
| 反応物 | Acipimox | HCID 5310993 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2-Carboxy-5-methylpyrazine 4-oxide ethanolamine salt | HCID 21408176 | 120.3% |
反応手順
2-Carboxy-5-methylpyrazine 4-oxide (2.5 g) was added to methanol (60 ml) and ethanolamine (1.1 ml). The mixture was refluxed for 20 minutes, then cooled and filtered to obtain 2-carboxy-5-methylpyrazine 4-oxide ethanolamine salt (2.1 g), m.p. 177°-180° C, after crystallisation from methanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04051245 |
| 出典データセット | uspto-grants-1977_09 |
| ORD ID | ord-d0005dc3fa04492e93be2da5511f0b34 |
| 出典メモ | uspto-grants-1977_09 |