Benzene → 3-methyl-4-(trichloroacetamido)phenyl N-methylcarbamate
反応式
[CH3:1][NH:2][C:3](=[O:13])[O:4][C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[C:7]([CH3:12])[CH:6]=1.C(N(CC)CC)C.C1C=CC=CC=1.[Cl:27][C:28]([Cl:33])([Cl:32])[C:29](Cl)=[O:30]>O>[CH3:1][NH:2][C:3](=[O:13])[O:4][C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:29](=[O:30])[C:28]([Cl:33])([Cl:32])[Cl:27])=[C:7]([CH3:12])[CH:6]=1参加物
6
実験手順
To a slurry of 3-methyl-4-aminophenyl N-methylcarbamate (1.8g., 0.01 mole), triethylamine (1.11g., 0.011 mole), and 25 ml. of benzene was added trichloroacetyl chloride (2.0g., 0.011 mole) dropwise. After refluxing for one hour, the reaction mixture was poured into water and the resulting solid product was filtered (3.05g., m.p. 185°-87° C.).
後処理
- temperatureAfter refluxing for one hour
- filtrationthe resulting solid product was filtered (3.05g., m.p. 185°-87° C.)
出典と根拠
- ORDレコード
- ord-a7cd5996b78b4f96bd4479f3e7a24945
- 出典データセット
- uspto-grants-1977_09
- 特許番号
- US04051254
反応ノート
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