Ammonia → HCID 178512021、化合物
反応式
[CH:1]1([NH:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=2)=S)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH3:18]>C(O)C>[CH:1]1([NH:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=2)=[NH:18])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1参加物
4
実験手順
1-Cyclohexyl-3-(p-chlorophenyl)thiourea (2.0 g.) was dissolved in absolute ethyl alcohol saturated with ammonia (40 ml.). To this was added yellow mercuric oxide (1.7 g.) and the mixture stirred at room temperature for 16 hours. The mixture was then refluxed 15 minutes to coagulate the fine precipitate of mercuric sulphide, filtered and the clear filtrate evaporated to dryness. The residue was recrystallised from toluene to give 1-cyclohexyl-3-(p-chlorophenyl)guanidine, m.p. 187°-190°.
後処理
- temperatureThe mixture was then refluxed 15 minutes
- filtrationfiltered
- customthe clear filtrate evaporated to dryness
- customThe residue was recrystallised from toluene
出典と根拠
- ORDレコード
- ord-98650856c0fb4485859013700ef65377
- 出典データセット
- uspto-grants-1977_09
- 特許番号
- US04051256
反応ノート
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