3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid → 3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride
反応式
[Cl:1][C:2]1[C:6]2=[N:7][C:8]([C:14]([OH:16])=[O:15])=[C:9]([C:11]([OH:13])=O)[CH:10]=[C:5]2[S:4][CH:3]=1>C(OC(=O)C)(=O)C>[Cl:1][C:2]1[C:6]2=[N:7][C:8]3[C:14](=[O:15])[O:16][C:11](=[O:13])[C:9]=3[CH:10]=[C:5]2[S:4][CH:3]=1参加物
3
実験手順
3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid (1.45 g) is heated at 85° to 90° C. for 30 minutes then 90° to 102° C. for 30 minutes in acetic anhydride (7 mL). The reaction is cooled, the solids filtered off and washed with ether to give 1.2 g of 3-chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride. The proton magnetic resonance spectrum is consistant with the structure.
後処理
- temperatureThe reaction is cooled
- filtrationthe solids filtered off
- washwashed with ether
出典と根拠
- ORDレコード
- ord-d36e90e6570340948e2cfd8d5d98e5e1
- 出典データセット
- uspto-grants-1990_04
- 特許番号
- US04920226
反応ノート
読み込み中…