Piperonal → 1,2-Bis(1,3-benzodioxol-5-yl)-2-hydroxyethanone
反応式
[CH:1]1[C:6]([CH:7]=[O:8])=[CH:5][C:4]2[O:9][CH2:10][O:11][C:3]=2[CH:2]=1.[C-]#N.[K+]>C(O)C.O>[CH2:10]1[O:11][C:3]2[CH:2]=[CH:1][C:6]([C:7]([CH:7]([C:6]3[CH:1]=[CH:2][C:3]4[O:11][CH2:10][O:9][C:4]=4[CH:5]=3)[OH:8])=[O:8])=[CH:5][C:4]=2[O:9]1参加物
5
実験手順
A solution of piperonal (5 g) in ethanol (6.5 ml) was treated with a solution of potassium cyanide (0.5 g) in water (5 ml), then refluxed for 5 h. The resultant precipitate was filtered off, washed with water then crystallized from ethanol to give DC-0001B (124 g, 45%) as an off white crystalline solid.
後処理
- temperaturerefluxed for 5 h
- filtrationThe resultant precipitate was filtered off
- washwashed with water
- customthen crystallized from ethanol
- customto give DC-0001B (124 g, 45%) as an off white crystalline solid
出典と根拠
- ORDレコード
- ord-ebcaddd64b5e49d5b646ae32b8c93ba3
- 出典データセット
- uspto-grants-2011_04
- 特許番号
- US07919530B2
反応ノート
読み込み中…