4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 67119077、化合物

反応式

Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2([C:11]([O:13][CH3:14])=[O:12])[CH2:10][CH2:9]2)=[CH:4][CH:3]=1.CC1(C)C(C)(C)OB([C:23]2[CH:28]=[CH:27][C:26]([OH:29])=[CH:25][CH:24]=2)O1>>[OH:29][C:26]1[CH:27]=[CH:28][C:23]([C:2]2[CH:7]=[CH:6][C:5]([C:8]3([C:11]([O:13][CH3:14])=[O:12])[CH2:10][CH2:9]3)=[CH:4][CH:3]=2)=[CH:24][CH:25]=1

参加物

反応物 2

HCID 27346244-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

HCID 46739795Methyl 1-(4-bromophenyl)cyclopropane-1-carboxylate

生成物 1

HCID 67119077HCID 67119077、化合物

実験手順

According to a method similar to Example (8-1), from methyl 1-(4-bromophenyl)cyclopropanecarboxylate (2.96 g, 11.6 mmol) obtained in Example (15-1) and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (2.55 g, 11.6 mmol), methyl 1-(4′-hydroxy-1,1′-biphenyl-4-yl)cyclopropanecarboxylate was obtained as a white powder (2.49 g, yield: 80%).

出典と根拠

ORDレコード: ord-f6210dd236624e95bc96acf08050997a
出典データセット: uspto-grants-2011_04
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07923573B2

反応ノート

読み込み中…

参加物