Hydrochloric Acid → 3-Fluorocatechol

HRID 2078529

反応式

HRID 2078529 の反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](I)[C:3]=1[OH:9].[OH-:10].[K+].Cl>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([OH:10])[C:3]=1[OH:9]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 222374962-Fluoro-6-iodophenol

生成物 1

HCID 677643-Fluorocatechol収率 78%

実験手順

To a 500 ml flask were added 119 g (0.5 mol) of 2-fluoro-6 -iodophenol and 200 ml of a 30% aqueous potassium hydroxide solution and they were reacted under vigorous stirring under a reflux temperature for 8 hours. After the termination of the reaction, the mixture was cooled to ordinary temperature and neutralized with hydrochloric acid to adjust pH between 2 and 3. After filtration, the filtrate was washed with water to obtain 49.9 g of a product [H]. The process yield was 78%.

後処理

  1. customwere reacted
  2. customAfter the termination of the reaction
  3. filtrationAfter filtration
  4. washthe filtrate was washed with water

出典と根拠

ORDレコード
ord-6ca3f3b8ce7d413ebc933d11b84e9835
出典データセット
uspto-grants-2011_04
特許番号
US07928268B2

関連ノート

読み込み中…