Hydrochloric Acid → HCID 23171545、化合物
反応式
Br[CH2:2][CH2:3][O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.[S:12]([O-])([O-:15])(=[O:14])=[O:13].[Na+].[Na+].Cl>O.C(O)C>[CH2:5]([O:4][CH2:3][CH2:2][S:12]([OH:15])(=[O:14])=[O:13])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1参加物
6
実験手順
A mixture of [(2-bromoethoxy)methyl]benzene (6.0 g) and sodium sulfate (3.9 g) in water (12 ml) and ethanol (36 ml) was refluxed overnight. The mixture was acidified with conc. hydrochloric acid under ice-cooling. The mixture was evaporated under reduced pressure. The residue was suspended in dichloromethane/methanol (4/1) and filtered off through Celite pad. The filtrate was evaporated to give 2-(benzyloxy)ethanesulfonic acid (4.5 g).
後処理
- temperaturewas refluxed overnight
- temperaturecooling
- customThe mixture was evaporated under reduced pressure
- filtrationfiltered off through Celite pad
- customThe filtrate was evaporated
出典と根拠
- ORDレコード
- ord-9cf1a4e8899546049ca054822f929375
- 出典データセット
- uspto-grants-2011_04
- 特許番号
- US07928264B2
反応ノート
読み込み中…