HCID 59516907、化合物 → HCID 59517045、化合物
反応式
[CH3:1][S:2][C:3](=[NH:25])[CH:4]([NH:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]#[N:24])=[CH:19][CH:18]=1)[C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[C:7]([O:13][CH3:14])[C:6]=1[F:15]>C(OCC)(=O)C.[O-2].[O-2].[Mn+4]>[CH3:1][S:2][C:3](=[NH:25])[C:4](=[N:16][C:17]1[CH:18]=[CH:19][C:20]([C:23]#[N:24])=[CH:21][CH:22]=1)[C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[C:7]([O:13][CH3:14])[C:6]=1[F:15]参加物
4
実験手順
After adding 4.95 g of manganese dioxide to a solution of 2.05 g of 2-(4-cyanophenylamino)-2-(2-fluoro-3,5-dimethoxyphenyl)thioacetimidic acid methyl ester in 100 ml of ethyl acetate, the mixture was stirred at room temperature for 3 hours. The reaction mixture was filtered through celite, and the celite was washed with 500 ml of ethyl acetate. The organic layers were combined and concentrated under reduced pressure. The title compound (2.01 g) was obtained as a light yellow solid.