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HRID 2079496作成日：2026年10月27日
Potassium Carbonate → 4-tert-Butyl-N-[4-chloro-2-(methoxy-pyridin-4-yl-methyl)-Phenyl]-benzenesulfonamide
https://huagongshe.com/reaction/2079496
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-tert-Butyl-N-[4-chloro-2-(chloro-pyridin-4-yl-methyl)-phenyl]-benzenesulfonamide | HCID 59485502 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 4-tert-Butyl-N-[4-chloro-2-(methoxy-pyridin-4-yl-methyl)-Phenyl]-benzenesulfonamide | HCID 59756865 | — |
反応手順
A suspension of 4-tert-butyl-N-[4-chloro-2-(chloro-pyridin-4-yl-methyl)-phenyl]-benzenesulfonamide (113 mg, 0.25 mmol) and potassium carbonate (69 mg, 0.5 mmol) in anhydrous methanol was heated at 60° C. overnight, the solid residue was then removed by filtration and product was purified by preparative HPLC. MS: (M+H)=445.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US07932252B2 |
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| 出典データセット | uspto-grants-2011_04 |
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| ORD ID | ord-8243154651194dda942bd5f33ca62a72 |
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| 出典メモ | uspto-grants-2011_04 |
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