化工社化工社 化学情報印刷レポート · 研究参考用
2-Nitro-4-trifluoromethylanisole → 2-Methoxy-5-(trifluoromethyl)aniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Nitro-4-trifluoromethylanisole | HCID 96748 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2-Methoxy-5-(trifluoromethyl)aniline | HCID 600637 | 99% |
反応手順
A mixture of 4-methoxy-3-nitrobenzotrifluoride and 10% of 10% Pd/C in methanol was stirred under H2 atmosphere overnight at room temperature. The reaction mixture was filtered through celite, concentrated and dried under vacuum to provide product as an off white solid in 99% yield. ES/MS m/z 192.1 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07932262B2 |
| 出典データセット | uspto-grants-2011_04 |
| ORD ID | ord-0e11a43a96194bd6b45518dc8d910a74 |
| 出典メモ | uspto-grants-2011_04 |