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3-(2-Methylpropenyl)-benzylamine → 3-Isobutylbenzylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(2-Methylpropenyl)-benzylamine | HCID 23130720 | — |
| 触媒 | HCID 178418390 | HCID 178418390 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-Isobutylbenzylamine | HCID 23130553 | 56.6% |
反応手順
3-(2-Methylpropenyl)-benzylamine described in Preparation Example 137 (100 mg, 0.621 mmol) was dissolved in ethanol (5 mL), 10% palladium-carbon (50% water wet, 20 mg) was added thereto, and the mixture was stirred for 2 hours at room temperature under hydrogen atmosphere. The catalyst was filtered, then, the solvent was evaporated, and the title compound (58 mg, 56.6%) was obtained as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07932272B2 |
| 出典データセット | uspto-grants-2011_04 |
| ORD ID | ord-f49fab2946984f2d92c5d12888688d44 |
| 出典メモ | uspto-grants-2011_04 |