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HRID 2080137作成日:2026年10月27日

3-(2-Methylpropenyl)-benzylamine → 3-Isobutylbenzylamine

https://huagongshe.com/reaction/2080137

反応式

関与物質

役割名称HCID仕込み量
反応物3-(2-Methylpropenyl)-benzylamineHCID 23130720—
触媒HCID 178418390HCID 178418390—
溶媒EthanolHCID 702—
生成物3-IsobutylbenzylamineHCID 2313055356.6%

反応手順

3-(2-Methylpropenyl)-benzylamine described in Preparation Example 137 (100 mg, 0.621 mmol) was dissolved in ethanol (5 mL), 10% palladium-carbon (50% water wet, 20 mg) was added thereto, and the mixture was stirred for 2 hours at room temperature under hydrogen atmosphere. The catalyst was filtered, then, the solvent was evaporated, and the title compound (58 mg, 56.6%) was obtained as a colorless oil.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07932272B2
出典データセットuspto-grants-2011_04
ORD IDord-f49fab2946984f2d92c5d12888688d44
出典メモuspto-grants-2011_04