1,2,3,4-Tetrahydroisoquinolin-8-amine → 8-Sulfamoyl-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline

反応式

[C:12](=[O:13])([CH3:14])[N:15]1[CH2:16][c:17]2[c:18]([S:29]([NH2:30])(=[O:31])=[O:32])[c:19]([C:25]([F:26])([F:27])[F:28])[cH:20][cH:21][c:22]2[CH2:23][CH2:24]1.[NH2:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[CH2:8][NH:9][CH2:10][CH2:11]2>>[NH:15]1[CH2:16][c:17]2[c:18]([S:29]([NH2:30])(=[O:31])=[O:32])[c:19]([C:25]([F:26])([F:27])[F:28])[cH:20][cH:21][c:22]2[CH2:23][CH2:24]1

参加物

反応物 2

HCID 205232091,2,3,4-Tetrahydroisoquinolin-8-amine

HCID 213938322-Acetyl-8-sulfamoyl-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline

生成物 1

HCID 213938378-Sulfamoyl-7-trifluoromethyl-1,2,3,4-tetrahydroisoquinoline

出典と根拠

ORDレコード: ord-2127abcc58e04653baeed17dcdd63af6
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…