1,4-Dibromobutane → HCID 20300322、化合物
反応式
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5]Br.[CH3:7][N:8]1[C:12](=[O:13])[C:11](=[O:14])[NH:10][C:9]1=[S:15]>>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][N:10]1[C:11](=[O:14])[C:12](=[O:13])[N:8]([CH3:7])[C:9]1=[S:15]参加物
3
実験手順
By the procedure of Example 1(i), 1,4-dibromobutane is reacted with 1-methyl-2-thioxo-4,5-imidazolidinedione to yield 1-(4-bromobutyl)-3-methyl-2-thioxo-4,5-imidazolidinedione which, on reaction with thiourea by the procedure of Example 1(ii) gives S-[4-(1-(3-methyl-4,5-dioxo-2-thioxoimidazolidinyl))butyl]isothiourea hydrobromide, m.p. 113°-114°. Hydrolysis of the latter compound and working up of the product by the general procedure of Example 1(iii) and conversion to the sulphate with ion-exchange resin (Amberlite IRA 400, sulphate form) gave the title product as a hygroscopic amorphous solid, m.p. 63°-65°.
出典と根拠
- ORDレコード
- ord-84bf8a3679c2402aa9be1e3c8f406cb9
- 出典データセット
- uspto-grants-1978_04
- 特許番号
- US04084001
反応ノート
読み込み中…