4-Bromo-2,2-diphenylbutyronitrile → HCID 20356983、化合物
反応式
Cl.[NH:2]1[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1.[C:8]1([C:14]([CH2:19][CH2:20][Cl:21])([CH2:17][CH3:18])[C:15]#[N:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.Cl.C12CCC(CC1)CN2.C1(C(C2C=CC=CC=2)(CCBr)C#N)C=CC=CC=1>>[ClH:21].[C:8]1([C:14]([CH2:19][CH3:20])([CH2:17][CH2:18][N:2]2[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]2)[C:15]#[N:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1参加物
5
実験手順
When equivalent quantities of piperidine hydrochloride and 2-phenyl-2-(2-chloroethyl)butyronitrile are substituted for the 2-azabicyclo[2.2.2]octane hydrochloride and 2,2-diphenyl-4-bromobutyronitrile used in Example 12, and the procedure described therein substantially repeated, there is obtained 2-phenyl-2-ethyl-4-piperidino-butyronitrile hydrochloride melting at about 200° - 203° C.